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RxNorm October 2023 Monthly Release

RxNorm October 2023 Monthly Release. NLM Tech Bull. 2023 Sep-Oct;(452):b9.

October 02, 2023 [posted]

The RxNorm October 2023 monthly release became available on Monday, October 2, 2023. We have made changes to Xacduro and some tacrolimus products for this release. 

RXNORM DATA CHANGES 

Changes to Xacduro

In response to the Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) feedback regarding issues with antimicrobial use surveillance and the modeling of Xacduro in RxNorm, we have changed Xacduro to a Semantic Branded Drug (SBD) for the RxNorm October 2023 monthly release. The concepts have new RXCUIs shown below.


New modeling:

RXCUI

TTY

STR

2665012

SCD

durlobactam 1000 MG / sulbactam 1000 MG Injection

2665017

SBD

durlobactam 1000 MG / sulbactam 1000 MG Injection [Xacduro]

 

Previous modeling:

RXCUI

TTY

STR

2639100

GPCK

{2 (durlobactam 500 MG Injection) / 1 (sulbactam 1000 MG Injection) } Pack

2639101

BPCK

{2 (durlobactam 500 MG Injection) / 1 (sulbactam 1000 MG Injection) } Pack [Xacduro]

 

Changes to Tacrolimus Products

The Food and Drug Administration (FDA) has changed the therapeutic equivalence rating of some tacrolimus products to BX. Based on feedback from our users, we have created new normal forms for those with the qualitative distinction of BX. 

The new forms are:

RXCUI

TTY

STR

2665161

SCD

BX Rating tacrolimus 0.5 MG Oral Capsule

2665162

SCD

BX Rating tacrolimus 1 MG Oral Capsule

2665163

SCD

BX Rating tacrolimus 5 MG Oral Capsule


The old forms are still available:

RXCUI

TTY

STR

313190

SCD

tacrolimus 0.5 MG Oral Capsule

198377

SCD

tacrolimus 1 MG Oral Capsule

198378

SCD

tacrolimus 5 MG Oral Capsule


For more information about the FDA’s decision see:
https://www.fda.gov/drugs/drug-safety-and-availability/fda-changing-therapeutic-equivalence-rating-accord-healthcare-incs-generics-prograf-tacrolimus-oral.