New Clinical Advisory Issued by National Institute of Neurological Disorders and Stroke (NINDS)

The National Institute of Neurological Disorders and Stroke (NINDS) issued a new Clinical Advisory on September 19, 2011:

Secondary Prevention of Small Subcortical Strokes Trial: NINDS Stops Treatment with Combination Antiplatelet Therapy (Clopidogrel plus Aspirin) Due to Higher Risk of Major Hemorrhage and Death

NINDS has stopped the combination antiplatelet intervention in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial. This was a randomized, multicenter clinical trial conducted throughout North America, Latin America and Spain, to learn about preventing a second stroke in patients who had a subcortical stroke and to learn how to prevent cognitive problems after a stroke.

Links to Clinical Alerts/Advisories can also be found from these NLM® Web sites:

• A complete list of all Clinical Alerts/Advisories is available from the NIH Clinical Alerts and Advisories page on the NLM Web site.
• MedlinePlus® features Clinical Alerts/Advisories as NIH Press Releases on the appropriate Health Topics page(s).
• PubMed®, the NLM Gateway and ClinicalTrials.gov each have access points to the Clinical Alerts/Advisories.

New Clinical Advisory Issued by National Institute of Neurological Disorders and Stroke (NINDS). NLM Tech Bull. 2011 Sep-Oct;(382):e6.