Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

This is a preview of updates coming to the Technical Bulletin's website in April 2026. Return to current site.
Read more about the modernization release schedule in this announcement.
Comment via the yellow feedback button in the lower right hand corner of the page. Contact the NLM Help Desk with any questions or concerns.

This is archived content.

Links may have become inactive over time. Visit Archive-It   to find the original published layout.

New Clinical Alert Issued by National Heart, Lung, and Blood Institute (NHLBI)

New Clinical Alert Issued by National Heart, Lung, and Blood Institute (NHLBI). NLM Tech Bull. 2011 Sep-Oct;(382):e15.

October 25, 2011 [posted]

The National Heart, Lung, and Blood Institute (NHLBI) issued a new Clinical Alert on October 21, 2011:

Commonly Used Three-drug Regimen for Idiopathic Pulmonary Fibrosis Found Harmful: NIH Stops One Treatment Arm of Trial; Other Two Treatments to Continue

NHLBI has stopped one arm of a three arm multi-center, clinical trial studying treatments for the lung-scarring disease idiopathic pulmonary fibrosis (IPF) for safety concerns. The trial found that people with IPF receiving a currently used triple-drug therapy consisting of prednisone, azathioprine, and N-acetylcysteine (NAC) had worse outcomes than those who received placebos or inactive substances.

Links to Clinical Alerts/Advisories can also be found from these NLM® Web sites: